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How does sildenafil work

Sildenafil is a medication that belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It is primarily used to treat erectile dysfunction (ED) in men, but it also has other medical uses. Sildenafil works by increasing blood flow to the penis, which helps men achieve and maintain an erection during sexual stimulation.

When a man is sexually aroused, nitric oxide is released in the erectile tissue of the penis, which stimulates the production of a chemical called cyclic guanosine monophosphate (cGMP). cGMP relaxes the smooth muscles in the blood vessels of the penis, allowing for increased blood flow and resulting in an erection.

Sildenafil inhibits the enzyme called phosphodiesterase type 5 (PDE5), which breaks down cGMP. By blocking the action of PDE5, sildenafil helps to prolong the effects of cGMP, leading to enhanced blood flow to the penis and improved erectile function.

It's worth noting that sildenafil is the active ingredient in the well-known brand Viagra, and it is also available as a generic medication. However, it's essential to consult with a healthcare professional before taking sildenafil or any medication to ensure it is suitable for your specific situation and to discuss potential risks and side effects.